Drug- induced

Estrogen/ anabolic steroids

Phenothiazines

TPN

Gram negative infections/sepsis

?endotoxin mediated

Benign post-op

Benign Recurrent Intrahepatic Cholestasis

Intrahepatic Cholestasis of preganancy

Familial forms

Arteriohepatic dysplasia (Allagille’s syndrome)

Byler’s disease

Traditionally hepatocellular disorders

Viral hepatitides

Rarely acute hep B in elderly

Hep C in transplant pts

Acute EtOH hepatitis (poor prognosis)

Miscellaneous

Sarcoid

Amyloid

HD/lymphoma (? mechanism)

Reference: Kelly’s Textbook of Internal Medicine, 3^rd edition, 1997.