Table of Contents
Treatment of Chronic Hepatitis C with Interferon: Historical perspectives and the data
Case presentation
Case presentation
Case presentation
Case presentation
Clinical Questions
Objectives
NIH Consensus Development Conference Panel Statement, September 1997 Hepatology; 26 (supplement): 2S-10S.
NIH Consensus Statement (cont’d)
NIH Consensus Statement (cont’d)
The Early Years...
1986: Preliminary study of IFN for NANB hepatitis Hoofnagle, et al. NEJM; 315: 1575-8
The Late 1980s: The breakthrough...
November, 1989: The first RCTs Davis, et al., N Engl J Med; 321: 1501-6.
November, 1989: The first RCTs Davis, et al., N Engl J Med; 321: 1501-6.
November, 1989: The first RCTs Davis, et al., N Engl J Med; 321: 1501-6.
November, 1989: The first RCTs Davis, et al., N Engl J Med; 321: 1501-6.
November, 1989: The first RCTs Davis, et al., N Engl J Med; 321: 1501-6.
November, 1989: The first RCTs DiBisceglie, et al., N Engl J Med; 321: 1506-10.
November, 1989: The first RCTs DiBisceglie, et al., N Engl J Med; 321: 1506-10.
November, 1989: The first RCTs DiBisceglie, et al., N Engl J Med; 321: 1506-10.
November, 1989: The first RCTs DiBisceglie, et al., N Engl J Med; 321: 1506-10.
November, 1989: The first RCTs DiBisceglie, et al., N Engl J Med; 321: 1506-10.
The early 1990s: The door opens...
Natural History
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1992-1997: Questions (and answers ?) abound...
1995: RCTs of dose and duration Poynard, et al., N Engl J Med; 332: 1457-62
1995: RCTs of dose and duration Poynard, et al., N Engl J Med; 332: 1457-62
1995: RCTs of dose and duration Poynard, et al., N Engl J Med; 332: 1457-62
1995: RCTs of dose and duration Poynard, et al., N Engl J Med; 332: 1457-62
1995: RCTs of dose and duration Poynard, et al., N Engl J Med; 332: 1457-62
1995: RCTs of dose and duration Lin, et al., J Hepatology; 23: 487-96.
1995: RCTs of dose and duration Lin, et al., J Hepatology; 23: 487-96.
1995: RCTs of dose and duration Lin, et al., J Hepatology; 23: 487-96.
1995: RCTs of dose and duration Lin, et al., J Hepatology; 23: 487-96.
1992-1997: Questions (and answers ?) abound...
1998: The future begins… Ribavirin and interferon
1998: The future begins… Ribavirin and interferon
1998: The future begins… Ribavirin and interferon
1998: The future begins… Ribavirin and interferon
1998: The future begins… Ribavirin and interferon
Conclusions, take home points, and what to tell my patient...
Conclusions, take home points, and what to tell my patient...
Conclusions, take home points, and what to tell my patient...
Conclusions, take home points, and what to tell my patient...
Treatment of Chronic Hepatitis C with Interferon
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Author: CLINT2
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