NSAIDS

In 1922, the association of ASA sensitivity, asthma, and nasal polyposis was described by Widal et al and was subsequently coined as the “aspirin triad.”

Aspirin-induced asthma (AIA) affects 10% of adults with asthma.
- After ingestion of ASA or an NSAID, an acute asthma attack occurs within 3 hrs, usually accompanied by profuse rhinorrhea, conjunctival injection, and periorbital edema.

In 1922, the association of ASA sensitivity, asthma, and nasal polyposis was described by Widal et al and was subsequently coined as the “aspirin triad.”