Stevenson et al
Between 1988 and 1994, 78 patients with asthma and documented ASA sensitivity per oral challenge (decrease of 20% or more in FEV1 and/or naso-ocular reactions within 3 hours of incremental oral challenges) were enrolled in a prospective study investigating ASA desensitization. 10 patients discontinued ASA desensitization treatment due to gastritis. 3 patients were lost to follow up. After desensitization, all patients began a treatment program of 650 mg of ASA twice daily, which was continued from 1 to 6 years (mean 3.1 years). Data was compared for 65 patients from the year prior to ASA desensitization and one year before re-evaluation (January to March 1995)