Hospitalized Adults cont.
Study - 8 centers who gave major and minor deteminants followed by PCN with 48 hr. observation in those with (-) tests. Pts. all had infections for which PCN was required.
1539 patients enrolled (1422 completed) - 825 had hx of PCN rxn (54%!) - 104 were unsure - 610 had no hx of PCN rxn