What about cephalosporins?

• Many physicians avoid cephalosporins is pt. is allergic to PCN. Cross-reactivity = 6-8%

• Type of Reaction FrequencyDermatologic 1.0-2.8%+ direct antiglobulin test 1.0-2.0%Anaphylaxis 0.0001-0.1%Fever 0.5-0.9%Eosinophilia 2.7-8.2%

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