Conclusions

Cephalosporins rarely cause anaphylactic reactions and can be used safely in most patients including those with penicillin allergy. Avoiding cephalosporins should be considered if patients have a known IgE-mediated reaction to penicillins.

Cephalosporins rarely cause anaphylactic reactions and can be used safely in most patients including those with penicillin allergy. Avoiding cephalosporins should be considered if patients have a known IgE-mediated reaction to penicillins.