| GUIDE |
COMMENTS |
| I.
BIOLOGIC: |
- Are there pathophysiologic differences in the
illness under study that may lead to a diminished treatment response?
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- Are there patient differences that may diminish
the treatment response?
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| II. SOCIAL AND ECONOMIC: |
- Are there important differences in patient
compliance that may diminish the treatment response?
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- Are there important differences in provider
compliance that may diminish the treatment response?
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| III.
EPIDEMIOLOGIC: |
- Do my patients have comorbid conditions that
significantly alter the potential benefits and risks of treatment?
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- Are there important differences in untreated
patients’ risk of adverse outcomes that might alter the efficiency of treatment?
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